Good news: Sarcoidosis research is growing!

Often we have sat back and wondered if anything could be done about sarcoidosis. Over the last few years the Foundation for Sarcoidosis Research has been offering research grants on an annual basis. While these subjects may be a bit “heady,” as you read you may discover words that have been thrown at you and little lights will go on as you see yourself being talked about. Have a good day, take a hug and pass it on.

2010: Kyra Oswald-Richter (Vanderbilt University)
Striking disparities exist in sarcoidosis clinical outcome. The Role of Differential Cytokine Production in Sarcoidosis Disease Pathogenesis will evaluate whether inadequate adaptive immune response contribute to disease progression in sarcoidosis. Learn More.

2009: Lobelia Samavati (Wayne State University)
Both environmental and genetic factors appear to play a role in sarcoidosis. The Role of Intracellular NOD-like Receptors in Sarcoidosis will investigate the role of specific proteins (cellular sensors which recognize pathogens) as well as to identify variants in the genes for the sensors. Learn more.

2008: Elliott Crouser (Ohio State University)
Some research has shown that nicotine suppresses the immune system and reduces inflammation characteristic of sarcoidosis in the lungs. Modulation of Pulmonary Sarcoidosis by Nicotinic Acetylcholine Receptors is a trial that will assess whether nicotine treatment (in patch form) will reduce the severity of lung disease. Learn more or Join the Trial.

2008: Edward Chen (Johns Hopkins University)
Recent studies have shown that genetic variations may be associated with an increased risk of developing sarcoidosis. The Role of Serum Amyloid A and RAGE in Sarcoidosis is designed to determine whether SAA and RAGE are important in the development of granulomatous inflammation. Read the 2010 Press Release about Findings.

2007: Michael Falta (University of Colorado Health Sciences Center)
T cell Ligands in Sarcoidosis focuses on understanding how immune blood cells, called T lymphocytes become overactivated in sarcoidosis patients and determining how they are involved in the formation of granulomas. This information might lead to an understanding of what causes disease and suggest new therapies for treating it.

2006: Richard Silver (Case Western Reserve University)*
Abnormal TLR Responses in the Pathogenesis of Pulmonary Sarcoidosis attempts to demonstrate that the response of specific infection recognizing molecules may be abnormal and contribute to the immune response in sarcoidosis. (*Received $50,000)

2006: Jan Wahlstrom (Karolinska University Hospital)
Identifying an antigen may provide clues to a cause, and potentially better treatments for this disease. Antigen specificity in Sarcoidosis focuses on a specific group of sarcoidosis patients whose immune system response may be related to exposure to a specific antigen, or foreign substance.

2005: Dan Culver (Cleveland Clinic)*
Matrix Metalloproteinases Contribute to Disease Progression in Pulmonary Sarcoidosis and Are Inhibited by PPar-γ focuses on lung cells in sarcoidosis patients – specifically low levels of a molecule (PPAR-γ) that regulates immune responses. If this molecule can be regulated, inflammation from sarcoidosis and similar inflammatory diseases could potentially be controlled. (*Received $50,000) Learn More.

2 thoughts on “Good news: Sarcoidosis research is growing!

  1. I have done tons of research about Sarcoidosis as my husband was dx with lymphatic sarc in 2004. Do you thing that any of these studies would allow for a specific product to be administered to patients to see if it helps reverse signs and symptoms of Sarcoidosis. there are 26 studies on pubmed that state “oxidative stress is the underlying pathology of sarcoidosis and other ILD’s”

    There is a natural remedy available right now that has done all things “supposedly” impossible for reversing his symptoms. It would be wonderful if there was a way to do a study on how it affects others with sarcoidosis. I would love to know how to contact these researchers and see if it could be possible. Thanks for posting this and look forward to helping find a cure, I just don’t think it will be through prescription drugs. Thanks again, Dani

  2. I would go to the web site

    taken from their page: FSR feels strongly that the causes of this disease, and ultimately a cure, will be uncovered through rigorous and extensive scientific research. Awards focus on collaborations which advance the understanding of sarcoidosis and address the causes of the disease, the suffering of patients and the potential for a cure for sarcoidosis.

    Wish you well.

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